Itachi Uchiha was also part of the Uchiha clan. The remanders were Madara Uchiha and Sasuke Uchiha. Sasuke has battled Itachi once, but did not defeat Itachi. The second time Sasuke had battled Itachi, Sasuke had finally won. Itachi was now dead. Itachi also killed the whole Uchiha clan. Madara helped Itachi kill the clan. Itachi had chosen not to kill Sasuke. Sasuke was devastated after the clan had died. Itachi was part of the Akatsuki, he had on his side was Kisame Hoshigaki.